Endothelial Dysfunction and Collagen Accumulation
نویسندگان
چکیده
منابع مشابه
Endothelial dysfunction and collagen accumulation: two independent factors for restenosis and constrictive remodeling after experimental angioplasty.
BACKGROUND Constrictive remodeling plays a prominent role in restenosis after balloon angioplasty, but its regulation remains unclear. Because endothelial dysfunction and changes in extracellular matrix have been reported after angioplasty, this study was designed to simultaneously evaluate endothelial function and collagen and elastin changes after restenosis and arterial remodeling. METHODS...
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to cause enhanced collagen accumulation by human embryonic lung fibroblasts (WI-38), as measured by hydroxyproline content of fibroblast monolayers, ["C] proline incorporation into soluble collagen and collagenase release of radioactivity in supernates and monolayers of cultures incubated with ["C] proline. This fibroblaststimulating activity, demonstrable by suitable dilutions of the supernate...
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ژورنال
عنوان ژورنال: Circulation
سال: 1999
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.100.10.1109